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CN427

CAS No.

CN427 ( CN-427;CN 427 )

Catalog No. M17055 CAS No.

CN427 (CN-427) is novel BRD4 (BD1, 2) inhibitor with IC50 of 66 nM, MV4-11 viability IC50 of 1.1 uM.

Purity : >98% (HPLC)

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Biological Information

Product Name

CN427
Note

Research use only, not for human use.
Brief Description

CN427 (CN-427) is novel BRD4 (BD1, 2) inhibitor with IC50 of 66 nM, MV4-11 viability IC50 of 1.1 uM.
Description

CN427 (CN-427) is novel BRD4 (BD1, 2) inhibitor with IC50 of 66 nM, MV4-11 viability IC50 of 1.1 uM.
Synonyms

CN-427;CN 427
Pathway

Chromatin/Epigenetic
Target

Bromodomain
Recptor

Bromodomain
Research Area

——
Indication

——

Chemical Information

CAS Number

--
Formula Weight

496.57
Molecular Formula

C28H28N6O3
Purity

>98% (HPLC)
Solubility

——
SMILES

OCCN1N=CC(C2=NC(N3C(C4=CC=CC=C4)COCC3)=C5C=C(C6=C(C)ON=C6C)C=CC5=N2)=C1
Chemical Name

2-(4-(6-(3,5-dimethylisoxazol-4-yl)-4-(3-phenylmorpholino)quinazolin-2-yl)-1H-pyrazol-1-yl)ethan-1-ol

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Yang SM, et al. Bioorg Med Chem Lett. 2018 Nov 15;28(21):3483-3488.

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