Cart
sales@molnova.com
CN427
CAS No.
CN427 ( CN-427;CN 427 )
Catalog No. M17055 CAS No.
CN427 (CN-427) is novel BRD4 (BD1, 2) inhibitor with IC50 of 66 nM, MV4-11 viability IC50 of 1.1 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameCN427
-
NoteResearch use only, not for human use.
-
Brief DescriptionCN427 (CN-427) is novel BRD4 (BD1, 2) inhibitor with IC50 of 66 nM, MV4-11 viability IC50 of 1.1 uM.
-
DescriptionCN427 (CN-427) is novel BRD4 (BD1, 2) inhibitor with IC50 of 66 nM, MV4-11 viability IC50 of 1.1 uM.
-
SynonymsCN-427;CN 427
-
PathwayChromatin/Epigenetic
-
TargetBromodomain
-
RecptorBromodomain
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number--
-
Formula Weight496.57
-
Molecular FormulaC28H28N6O3
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESOCCN1N=CC(C2=NC(N3C(C4=CC=CC=C4)COCC3)=C5C=C(C6=C(C)ON=C6C)C=CC5=N2)=C1
-
Chemical Name2-(4-(6-(3,5-dimethylisoxazol-4-yl)-4-(3-phenylmorpholino)quinazolin-2-yl)-1H-pyrazol-1-yl)ethan-1-ol
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Yang SM, et al. Bioorg Med Chem Lett. 2018 Nov 15;28(21):3483-3488.
molnova catalog
related products
-
JQ1
(+)-JQ-1 (JQ1) is a potent, selective, cell-permeable BET bromodomain inhibitor with IC50 of 77 nM/33 nM for BRD4 BD1 and BD2, respectively.
-
GNE-781
GNE-781 (GNE781) is a potent, selective, non-CNS penetrant, orally active CBP/p300 bromodomain inhibitor.
-
GSK4027
GSK4027 (GSK 4027, GSK-4027) is a potent, selective, cell-penetrant chemical probe of PCAF/GCN5 bromodomain with pKi of 8.9 for both.
