BC-1382

CAS No. 1013753-99-5

BC-1382 ( —— )

Catalog No. M22211 CAS No. 1013753-99-5

BC-1382 is a potent ubiquitin E3 ligase HECTD2 inhibitor that specificly disrupts the HECTD2/PIAS1 interaction(IC50 of 5 nM).BC-1382, that targeted HECTD2 and attenuated lipopolysaccharide (LPS)- and Pseudomonas aeruginosa-induced lung inflammation.?

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 201 In Stock
10MG 299 In Stock
25MG 507 In Stock
50MG 731 In Stock
100MG 1017 In Stock
500MG 2034 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    BC-1382
  • Note
    Research use only, not for human use.
  • Brief Description
    BC-1382 is a potent ubiquitin E3 ligase HECTD2 inhibitor that specificly disrupts the HECTD2/PIAS1 interaction(IC50 of 5 nM).BC-1382, that targeted HECTD2 and attenuated lipopolysaccharide (LPS)- and Pseudomonas aeruginosa-induced lung inflammation.?
  • Description
    BC-1382 is a potent ubiquitin E3 ligase HECTD2 inhibitor that specificly disrupts the HECTD2/PIAS1 interaction(IC50 of 5 nM).BC-1382, that targeted HECTD2 and attenuated lipopolysaccharide (LPS)- and Pseudomonas aeruginosa-induced lung inflammation.?
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ubiquitin E3 ligase HECTD2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1013753-99-5
  • Formula Weight
    459.56
  • Molecular Formula
    C23H29N3O5S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    COc1ccccc1CNC(=O)[C@H](C)NC(=O)C1CCN(CC1)S(=O)(=O)c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Coon T A , Mckelvey A C , Lear T , et al. The proinflammatory role of HECTD2 in innate immunity and experimental lung injury[J]. ence Translational Medicine, 2015, 7(295):295ra109.
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