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BC-1382

CAS No. 1013753-99-5

BC-1382 ( —— )

Catalog No. M22211 CAS No. 1013753-99-5

BC-1382 is a potent ubiquitin E3 ligase HECTD2 inhibitor that specificly disrupts the HECTD2/PIAS1 interaction(IC50 of 5 nM).BC-1382, that targeted HECTD2 and attenuated lipopolysaccharide (LPS)- and Pseudomonas aeruginosa-induced lung inflammation.?

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    BC-1382
  • Note
    Research use only, not for human use.
  • Brief Description
    BC-1382 is a potent ubiquitin E3 ligase HECTD2 inhibitor that specificly disrupts the HECTD2/PIAS1 interaction(IC50 of 5 nM).BC-1382, that targeted HECTD2 and attenuated lipopolysaccharide (LPS)- and Pseudomonas aeruginosa-induced lung inflammation.?
  • Description
    BC-1382 is a potent ubiquitin E3 ligase HECTD2 inhibitor that specificly disrupts the HECTD2/PIAS1 interaction(IC50 of 5 nM).BC-1382, that targeted HECTD2 and attenuated lipopolysaccharide (LPS)- and Pseudomonas aeruginosa-induced lung inflammation.?
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ubiquitin E3 ligase HECTD2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1013753-99-5
  • Formula Weight
    459.56
  • Molecular Formula
    C23H29N3O5S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    COc1ccccc1CNC(=O)[C@H](C)NC(=O)C1CCN(CC1)S(=O)(=O)c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Coon T A , Mckelvey A C , Lear T , et al. The proinflammatory role of HECTD2 in innate immunity and experimental lung injury[J]. ence Translational Medicine, 2015, 7(295):295ra109.
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