Ac-KQKLR-AMC (Cathepsin S substrate) is a biological active peptide. (Cathepsins are a class of globular lysosomal proteases, playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin S is a cysteine proteinase involved in the pathogenesis of autoimmune diseases, atherosclerosis, cancer, obesity and related diseases.This peptide is a cathepsin S substrate fluorescently labeled with AMC (Ex/Em=354 nm/442 nm). It can be used to measure cathepsin S activity.)

N-Acetaminophen is a methylated form of Colchicine.

KPT-6566 is a novel selective covalent pin1 inhibitor KPT-6566 shows an IC50 of 640?nM and a Ki of 625.2 nM for PIN1 PPIase domainand has anti-cancer activity.