Cart
sales@molnova.com
Aβ42-IN-2
CAS No. 1914989-80-2
Aβ42-IN-2( —— )
Catalog No. M37643 CAS No. 1914989-80-2
Aβ42-IN-2, a γ-secretase modulator with an IC50 of 6.5 nM for Αβ42, can be used for Alzheimer's disease research .
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 88 | Get Quote |
|
| 5MG | 136 | Get Quote |
|
| 10MG | 215 | Get Quote |
|
| 25MG | 347 | Get Quote |
|
| 50MG | 492 | Get Quote |
|
| 100MG | 664 | Get Quote |
|
| 500MG | 1332 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameAβ42-IN-2
-
NoteResearch use only, not for human use.
-
Brief DescriptionAβ42-IN-2, a γ-secretase modulator with an IC50 of 6.5 nM for Αβ42, can be used for Alzheimer's disease research .
-
DescriptionAβ42-IN-2 is a γ-secretase modulator extracted from patent WO2016070107, compound example 36. Aβ42-IN-2 has an IC50 of 6.5 nM for Αβ42.Aβ42-IN-2 can be used for the research of Alzheimer's disease.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayNeuroscience
-
TargetGamma-secretase
-
RecptorGamma-secretase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1914989-80-2
-
Formula Weight430.5
-
Molecular FormulaC24H26N6O2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 20 mg/mL (46.46 mM; Ultrasonic )
-
SMILESCOc1ccc(cc1)[C@H](C)Nc1nnc(cc1C)-c1ccc(c(OC)n1)-n1cnc(C)c1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Steven L. Wagner, et al. Potent gamma-secretase modulators. WO2016070107A1.
molnova catalog
related products
-
Genz-123346 free bas...
Genz 123346 is an inhibitor of GL1 synthase that blocks the conversion of ceramide to GL1.
-
Jagged-1 188-204
This peptide is a fragment of the JAG-1 protein. JAG-1 is Notch ligand, a peptide that is the most conspicuously expressed ligand in skin. JAG-1 induces epidermal maturation. Exposing submerged keratinocytes monolayers to JAG-1 with elevated calcium concentration produces stratification with loricrin expression and NF-αB activation.
-
RBPJ Inhibitor-1
RBPJ Inhibitor-1 (RIN1), a compound that impedes the functional interaction between RBPJ and SHARP, effectively inhibits NOTCH-dependent tumor cell proliferation.
