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Azosemide

CAS No. 27589-33-9

Azosemide ( —— )

Catalog No. M26067 CAS No. 27589-33-9

Azosemide is a potent NKCC1 inhibitor (IC50s: 0.246?μM and 0.197?μM for hNKCC1A and NKCC1B).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Azosemide
  • Note
    Research use only, not for human use.
  • Brief Description
    Azosemide is a potent NKCC1 inhibitor (IC50s: 0.246?μM and 0.197?μM for hNKCC1A and NKCC1B).
  • Description
    Azosemide is a potent NKCC1 inhibitor (IC50s: 0.246?μM and 0.197?μM for hNKCC1A and NKCC1B).(In Vitro):Azosemide inhibits the sodium-potassium-chloride-cotransporter human variants hNKCC1B and hNKCC1A .(In Vivo):Azosemide shows a shorter terminal half-life (50.9% decrease) and MRT (64.1% decrease), smaller AUC (81.9% decrease), faster CL (454% increase), CLNR (307% increase) and CLR (853% increase) for NARs .
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    27589-33-9
  • Formula Weight
    370.8
  • Molecular Formula
    C12H11ClN6O2S2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    NS(=O)(=O)c1cc(-c2nnn[nH]2)c(NCc2cccs2)cc1Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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