Atipamezole ( MPV-1248;MPV1248;MPV 1248 )

Catalog No. M10207 CAS No. 104054-27-5

Antipamezole (MPV-1248) is a potent, specific α2-adrenoceptor antagonist with Ki of 1.6 nM.

Purity : >98% (HPLC)

COA

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Biological Information

Product Name

Atipamezole
Note

Research use only, not for human use.
Brief Description

Antipamezole (MPV-1248) is a potent, specific α2-adrenoceptor antagonist with Ki of 1.6 nM.
Description

Antipamezole (MPV-1248) is a potent, specific α2-adrenoceptor antagonist with Ki of 1.6 nM; reverses the effects of the sedative dexmedetomidine and medetomidine as a veterinary drug.Alcoholism Phase 1 Discontinued
Synonyms

MPV-1248;MPV1248;MPV 1248
Pathway

Angiogenesis
Target

Adrenergic Receptor
Recptor

α2-adrenoceptor
Research Area

Neurological Disease
Indication

Alcoholism

Chemical Information

CAS Number

104054-27-5
Formula Weight

212.29
Molecular Formula

C14H16N2
Purity

>98% (HPLC)
Solubility

DMSO: ≥30 mg/mL
SMILES

CCC1(C2=CNC=N2)CC3=C(C=CC=C3)C1
Chemical Name

1H-Imidazole, 5-(2-ethyl-2,3-dihydro-1H-inden-2-yl)-

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Pertovaara A, et al. CNS Drug Rev. 2005 Autumn;11(3):273-88.
2. Scheinin H, et al. Eur J Pharmacol. 1988 Jun 22;151(1):35-42.
3. Scheinin H, et al. Eur J Pharmacol. 1986 Sep 23;129(1-2):113-21.
4. Karhuvaara S, et al. Br J Clin Pharmacol. 1990 Jul;30(1):97-106.

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