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Asunaprevir

CAS No. 630420-16-5

Asunaprevir( BMS-650032 | BMS650032 | Asunaprevir )

Catalog No. M18929 CAS No. 630420-16-5

Asunaprevir is an effective hepatitis C virus (HCV) NS3 protease inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 61 In Stock
5MG 102 In Stock
10MG 170 In Stock
25MG 336 In Stock
50MG 512 In Stock
100MG 737 In Stock
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Biological Information

  • Product Name
    Asunaprevir
  • Note
    Research use only, not for human use.
  • Brief Description
    Asunaprevir is an effective hepatitis C virus (HCV) NS3 protease inhibitor.
  • Description
    Asunaprevir, also known as BMS-650032, is an inhibitor of the hepatitis C virus enzyme serine protease NS3. Asunaprevir is being tested in combination with pegylated interferon and ribavirin, as well as in interferon-free regimens with other direct-acting antiviral agents including daclatasvir.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    BMS-650032 | BMS650032 | Asunaprevir
  • Pathway
    JAK/STAT Signaling
  • Target
    STAT
  • Recptor
    HCV NS3/4A protease
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    630420-16-5
  • Formula Weight
    748.29
  • Molecular Formula
    C35H46ClN5O9S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 42.9 mg/mL; 57.33 mM
  • SMILES
    O=C([C@@H](NC(=O)OC(C)(C)C)C(C)(C)C)N5C[C@H](Oc1ncc(OC)c2ccc(Cl)cc12)C[C@H]5C(=O)N[C@@]3(C[C@H]3C=C)C(=O)NS(=O)(=O)C4CC4
  • Chemical Name
    1,1-dimethylethyl ((1S)-1-{((2S,4R)-4-(7-chloro-4-methoxyisoquinolin-1-yloxy)-2-({(1R,2S)-1-((cyclopropylsulfonyl)carbamoyl)-2-ethenylcyclopropyl}carbamoyl) pyrrolidin-1-yl)carbonyl}-2,2-dimethylpropyl)carbamate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Pelosi LA, et al. Effect on HCV Replication by Combinations of Direct Acting Antivirals Including NS5A Inhibitor Daclatasvir. Antimicrob Agents Chemother. 2012 Jul 30.
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