Astragalin ( Astragalin; Astragaline; K5;Kaempferol-3-O-glucoside )

Catalog No. M18607 CAS No. 480-10-4

COA

Datasheet

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Product Name

Astragalin
Note

Research use only, not for human use.
Brief Description

Astragalin can be effective in allaying ROS-promoted bronchial fibrosis through inhibiting autophagosome formation in airways.
Description

Astragalin is a flavonoid with anti-inflammatory activity. Astragalin inhibits IL-1β-stimulated nitric oxide and prostaglandin E2 (PGE2) production in patient-derived osteoarthritis chondrocytes. It also inhibits IL-1β-stimulated expression of nitric oxide synthase (NOS) and COX-2 and activation of MAPK and NF-κB signaling. Astragalin also reduces reactive oxygen species (ROS) production, collagen fiber deposition, and autophagosome formation in the epithelial lung tissue of ovalbumin-challenged mice.
Synonyms

Astragalin; Astragaline; K5;Kaempferol-3-O-glucoside
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Inflammation/Immunology
Indication

——

CAS Number

480-10-4
Formula Weight

448.38
Molecular Formula

C21H20O11
Purity

98%
Solubility

DMSO : ≥ 100 mg/mL; 223.03 mM
SMILES

C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)CO)O)O)O)O
Chemical Name

4H-1-Benzopyran-4-one, 3-(beta-D-glucopyranosyloxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-