
Aripiprazole
CAS No. 129722-12-9
Aripiprazole( OPC 31 | OPC 14597 )
Catalog No. M11199 CAS No. 129722-12-9
Aripiprazole(Abilify) is a human 5-HT1A receptor partial agonist with a Ki of 4.2 nM.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
100MG | 52 | In Stock |
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200MG | 68 | In Stock |
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500MG | 93 | In Stock |
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1G | 122 | In Stock |
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Biological Information
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Product NameAripiprazole
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NoteResearch use only, not for human use.
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Brief DescriptionAripiprazole(Abilify) is a human 5-HT1A receptor partial agonist with a Ki of 4.2 nM.
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DescriptionAripiprazole(Abilify) is a human 5-HT1A receptor partial agonist with a Ki of 4.2 nM.(In Vitro):Aripiprazole potently activates D2 receptor-mediated inhibition of cAMP accumulation.Aripiprazole shows a greater anti-inflammatory effect on TNF-α, IL-13, IL-17α and fractalkine.(In Vivo):Aripiprazole (0-3 mg/kg, IP, daily) shows some anxiolytic properties.
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In VitroAripiprazole potently activates D2 receptor-mediated inhibition of cAMP accumulation.Aripiprazole shows a greater anti-inflammatory effect on TNF-α, IL-13, IL-17α and fractalkine.
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In VivoAripiprazole (0-3 mg/kg, IP, daily) shows some anxiolytic properties. Animal Model:WAG/Rij rats (N = 6 per dose, 6 months, administration of a mixture of tiletamine/zolazepam)Dosage:0, 0.3, 1, 3 mg/kg Administration:IP, 1 mL/kg, every day at 5 p.m. until the end of the experiments Result:Showed some anxiolytic properties with the 1 mg/kg dose being the most active.
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SynonymsOPC 31 | OPC 14597
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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Recptor5-HT1A
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number129722-12-9
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Formula Weight448.39
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Molecular FormulaC23H27Cl2N3O2
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Purity>98% (HPLC)
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SolubilityDMSO: 90 mg/mL (200.71 mM)
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SMILESC1CC(=O)NC2=C1C=CC(=C2)OCCCCN3CCN(CC3)C4=C(C(=CC=C4)Cl)Cl
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Chemical Name7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Nasrallah HA. Mol Psychiatry. 2008 Jan;13(1):27-35.
molnova catalog



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