Argatroban

CAS No. 74863-84-6

Argatroban( MCI-9038 )

Catalog No. M15853 CAS No. 74863-84-6

Argatroban is a direct, selective thrombin inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 53 In Stock
10MG 69 In Stock
25MG 129 In Stock
50MG 201 In Stock
100MG 281 In Stock
200MG 419 In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    Argatroban
  • Note
    Research use only, not for human use.
  • Brief Description
    Argatroban is a direct, selective thrombin inhibitor.
  • Description
    Argatroban is a direct, selective thrombin inhibitor. The American College of Cardiologists (ACC) recommend using bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and are undergoing percutaneous coronary intervention. Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients with HIT and prevent the formation of thrombi. Parental anticoagulants must be stopped and a baseline activated partial thromboplastin time must be obtained prior to administering argatroban.
  • In Vitro
    Argatroban (MD-805) may have a complementary effect for preventing thrombus formation without aggravating bleeding tendency because of its monotarget specificity to thrombin. Administration (0.5 to 2 micrograms/kg/min) of Argatroban (MD-805) is a safe anticoagulant for left heart bypass in repairs of traumatic aortic rupture associated with multiple organ injuries. Argatroban (MD-805), as compared with heparin, appears to enhance reperfusion with TPA in patients with AMI, particularly in those patients with delayed presentation. The incidences of major bleeding and adverse clinical outcome were lower in the patients receiving argatroban.
  • In Vivo
    ——
  • Synonyms
    MCI-9038
  • Pathway
    Autophagy
  • Target
    Thrombin
  • Recptor
    Thrombin
  • Research Area
    Cardiovascular Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    74863-84-6
  • Formula Weight
    508.63
  • Molecular Formula
    C23H36N6O5S
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 6 mg/mL (11.79 mM); DMSO: 9 mg/mL (17.69 mM)
  • SMILES
    C[C@@H]1CCN([C@H](C1)C(=O)O)C(=O)[C@H](CCCN=C(N)N)NS(=O)(=O)C2=CC=CC3=C2NCC(C3)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kawada T, et al. Jpn J Thorac Cardiovasc Surg. 1999 Mar;47(3):104-9.
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