
Andarine
CAS No. 401900-40-1
Andarine( GTx-007 | S-4 | GTx007 )
Catalog No. M14376 CAS No. 401900-40-1
Andarine (S-4;GTx007) is a non-steroidal selective androgen receptor modulator (SARM) with Ki of 4 nM.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
5MG | 49 | In Stock |
![]() ![]() |
10MG | 69 | In Stock |
![]() ![]() |
50MG | 135 | In Stock |
![]() ![]() |
100MG | Get Quote | In Stock |
![]() ![]() |
200MG | Get Quote | In Stock |
![]() ![]() |
500MG | Get Quote | In Stock |
![]() ![]() |
1G | Get Quote | In Stock |
![]() ![]() |
Biological Information
-
Product NameAndarine
-
NoteResearch use only, not for human use.
-
Brief DescriptionAndarine (S-4;GTx007) is a non-steroidal selective androgen receptor modulator (SARM) with Ki of 4 nM.
-
DescriptionAndarine (S-4;GTx007) is a non-steroidal selective androgen receptor modulator (SARM) with Ki of 4 nM, efficaciously stimulated AR-mediated reporter gene expression; demonstrates in vivo androgenic and anabolic activity, stimulates the anabolic organs more than the androgenic organs; improves muscle strength and body composition and prevents bone loss in orchidectomized rats.(In Vivo):GTx-007 (S-4) is only a partial agonist in the prostate and seminal vesicles, restoring them to 33.8 and 28.2% of intact animals, respectively.GTx-007 significantly increased uterine expression of Wnt4 and Wnt7a.
-
In Vitro——
-
In VivoGTx-007 (S-4) is only a partial agonist in the prostate and seminal vesicles, restoring them to 33.8 and 28.2% of intact animals, respectively.GTx-007 significantly increased uterine expression of Wnt4 and Wnt7a. Animal Model:Female C57BL/6J mice.Dosage:0.5?mg/mouse.Administration:Seven daily subcutaneous injections.Result:Resulted in a highly heterogeneous pattern of AR expression in all compartments, with a significant increase of AR-positive cells in the luminal epithelium compared to VC.Had approximately ten glands per uterine cross-section within an endometrium, with a compact stroma, consistent with overall endogenous steroid depletion.
-
SynonymsGTx-007 | S-4 | GTx007
-
PathwayEndocrinology/Hormones
-
TargetAndrogen Receptor (AR)
-
RecptorAndrogenReceptor
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number401900-40-1
-
Formula Weight441.3579
-
Molecular FormulaC19H18F3N3O6
-
Purity>98% (HPLC)
-
Solubility10 mM in DMSO
-
SMILESO=C(NC1=CC=C([N+]([O-])=O)C(C(F)(F)F)=C1)[C@@](C)(O)COC2=CC=C(NC(C)=O)C=C2
-
Chemical NamePropanamide, 3-[4-(acetylamino)phenoxy]-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-, (2S)-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Kearbey JD, et al. Xenobiotica. 2004 Mar;34(3):273-80.
2. Gao W, et al. Endocrinology. 2005 Nov;146(11):4887-97.
3. Yin D, et al. J Pharmacol Exp Ther. 2003 Mar;304(3):1334-40.
4. Kearbey JD, et al. Pharm Res. 2007 Feb;24(2):328-35.
molnova catalog



related products
-
Andarine
Andarine (S-4;GTx007) is a non-steroidal selective androgen receptor modulator (SARM) with Ki of 4 nM.
-
RD162
RD162 is a second-generation, orally available antiandrogen that binds to androgen receptor (AR) with IC50 of 30.9 nM.
-
Epiandrosterone
Epiandrosterone is a steroid hormone with weak androgenic activity, is a natural metabolite of DHEA.