Amprenavir ( VX-478;141W94 )

Catalog No. M12371 CAS No. 161814-49-9

A potent HIV-1 protease inhibitor with IC50 of 80 nM, has mean IC50 of 12 nM against 6 HIV clinical isolates.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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10MG	73	In Stock
25MG	147	In Stock
50MG	260	In Stock
100MG	385	In Stock
500MG	872	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Amprenavir
Note

Research use only, not for human use.
Brief Description

A potent HIV-1 protease inhibitor with IC50 of 80 nM, has mean IC50 of 12 nM against 6 HIV clinical isolates.
Description

A potent HIV-1 protease inhibitor with IC50 of 80 nM, has mean IC50 of 12 nM against 6 HIV clinical isolates; shows synergistic effect with a variety of anti-HIV-1 agents and exhibits a unique cross resistance profile.HIV Infection Approved
Synonyms

VX-478;141W94
Pathway

Microbiology/Virology
Target

HIV
Recptor

HIVprotease
Research Area

Infection
Indication

HIV Infection

Chemical Information

CAS Number

161814-49-9
Formula Weight

505.63
Molecular Formula

C25H35N3O6S
Purity

>98% (HPLC)
Solubility

10 mM in DMSO
SMILES

CC(C)CN(CC(C(CC1=CC=CC=C1)NC(=O)OC2CCOC2)O)S(=O)(=O)C3=CC=C(C=C3)N
Chemical Name

Carbamic acid, N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, (3S)-tetrahydro-3-furanyl ester

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. St Clair MH, et al. Antiviral Res. 1996 Jan;29(1):53-6.
2. Partaledis JA, et al. J Virol. 1995 Sep;69(9):5228-35.
3. Markland W, et al. J Virol. 2000 Aug;74(16):7636-41.

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