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Amprenavir
CAS No. 161814-49-9
Amprenavir ( VX-478;141W94 )
Catalog No. M12371 CAS No. 161814-49-9
A potent HIV-1 protease inhibitor with IC50 of 80 nM, has mean IC50 of 12 nM against 6 HIV clinical isolates.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 41 | In Stock |
|
| 10MG | 73 | In Stock |
|
| 25MG | 147 | In Stock |
|
| 50MG | 260 | In Stock |
|
| 100MG | 385 | In Stock |
|
| 500MG | 872 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAmprenavir
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NoteResearch use only, not for human use.
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Brief DescriptionA potent HIV-1 protease inhibitor with IC50 of 80 nM, has mean IC50 of 12 nM against 6 HIV clinical isolates.
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DescriptionA potent HIV-1 protease inhibitor with IC50 of 80 nM, has mean IC50 of 12 nM against 6 HIV clinical isolates; shows synergistic effect with a variety of anti-HIV-1 agents and exhibits a unique cross resistance profile.HIV Infection Approved
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SynonymsVX-478;141W94
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PathwayMicrobiology/Virology
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TargetHIV
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RecptorHIVprotease
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Research AreaInfection
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IndicationHIV Infection
Chemical Information
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CAS Number161814-49-9
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Formula Weight505.63
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Molecular FormulaC25H35N3O6S
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESCC(C)CN(CC(C(CC1=CC=CC=C1)NC(=O)OC2CCOC2)O)S(=O)(=O)C3=CC=C(C=C3)N
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Chemical NameCarbamic acid, N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, (3S)-tetrahydro-3-furanyl ester
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. St Clair MH, et al. Antiviral Res. 1996 Jan;29(1):53-6.
2. Partaledis JA, et al. J Virol. 1995 Sep;69(9):5228-35.
3. Markland W, et al. J Virol. 2000 Aug;74(16):7636-41.
2. Partaledis JA, et al. J Virol. 1995 Sep;69(9):5228-35.
3. Markland W, et al. J Virol. 2000 Aug;74(16):7636-41.
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