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Aminooxy-PEG4-alcohol
Aminooxy-PEG4-alcohol
CAS No. 106492-60-8
Aminooxy-PEG4-alcohol( —— )
Catalog No. M33266 CAS No. 106492-60-8
Aminooxy-PEG4-alcohol is both a non-cleavable 4-unit PEG ADC linker and a PEG-based PROTAC linker.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 46 | In Stock |
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| 5MG | 44 | In Stock |
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| 10MG | 65 | In Stock |
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| 25MG | 109 | In Stock |
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| 50MG | 162 | In Stock |
|
| 100MG | 268 | In Stock |
|
| 200MG | 358 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAminooxy-PEG4-alcohol
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NoteResearch use only, not for human use.
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Brief DescriptionAminooxy-PEG4-alcohol is both a non-cleavable 4-unit PEG ADC linker and a PEG-based PROTAC linker.
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DescriptionAminooxy-PEG4-alcohol is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Aminooxy-PEG4-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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In VitroADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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Synonyms——
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PathwayAntibody Drug Conjugates (ADC)
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TargetADCs Linker/Click Chemistry
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RecptorADC Linker | PROTAC Linker
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Research Area——
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Indication——
Chemical Information
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CAS Number106492-60-8
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Formula Weight209.24
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Molecular FormulaC8H19NO5
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Purity>98% (HPLC)
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Solubility——
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SMILESC(OCCOCCO)COCCON
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Heather D. Maynard, et al. Method of creating hydrogels through oxime bond formation. US20150202305A1.
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