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Amino-PEG12-acid

CAS No. 1415408-69-3

Amino-PEG12-acid( —— )

Catalog No. M26881 CAS No. 1415408-69-3

Amino-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Amino-PEG12-acid
  • Note
    Research use only, not for human use.
  • Brief Description
    Amino-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
  • Description
    Amino-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    NUDT5
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1415408-69-3
  • Formula Weight
    617.73
  • Molecular Formula
    C27H55NO14
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 12.5 mg/mL (20.24 mM)
  • SMILES
    NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Page BDG, et al. Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells [published correction appears in Nat Commun. 2019 Nov 1;10(1):5050]. Nat Commun. 2018;9(1):250.
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