Amifostine

CAS No. 20537-88-6

Amifostine( Amifostine )

Catalog No. M13186 CAS No. 20537-88-6

Amifostine is a cytoprotective adjuvant used in Y chemotherapy and radiotherapy involving DNA-binding chemotherapeutic agents.

Amifostine is a cytoprotective adjuvant used in Y chemotherapy and radiotherapy involving DNA-binding chemotherapeutic agents.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 28 In Stock
10MG 41 In Stock
25MG 97 In Stock
50MG 180 In Stock
100MG 300 In Stock
200MG 447 In Stock
500MG 716 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Amifostine
  • Note
    Research use only, not for human use.
  • Brief Description
    Amifostine is a cytoprotective adjuvant used in Y chemotherapy and radiotherapy involving DNA-binding chemotherapeutic agents.
  • Description
    Amifostine is a cytoprotective adjuvant used in Y chemotherapy and radiotherapy involving DNA-binding chemotherapeutic agents.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Male C57BL/6 mice with myocardial I/R injury Dosage:400 mg/kg Administration:Intravenous injection; 4 hours Result:Attenuated cardiomyocyte apoptosis and reduced the production of I/R-induced ROS. Significantly reduced the expression of cleaved caspase 3 and Bax whileenhanced the expression of SOD1, SOD2 and Bcl2.Significantly increased SOD activity and reduced MDA levels.
  • Synonyms
    Amifostine
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    20537-88-6
  • Formula Weight
    214.22
  • Molecular Formula
    C5H15N2O3PS
  • Purity
    >98% (HPLC)
  • Solubility
    Soluble in Water
  • SMILES
    NCCCNCCSP(O)(O)=O
  • Chemical Name
    2-((3-Aminopropyl)amino)-ethanethiol, dihydrogen phosphate ester (9CI)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kouvaris JR. Oncologist. 12 (6): 738–47
molnova catalog
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