Phloretin

CAS No. 60-82-2

Phloretin ( NSC 407292; RJC 02792 )

Catalog No. M18884 CAS No. 60-82-2

Phloretin is a well-known inhibitor of eukaryotic urea transporters, blocks VacA-mediated urea and ion transport.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
500MG 51 In Stock
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Biological Information

  • Product Name
    Phloretin
  • Note
    Research use only, not for human use.
  • Brief Description
    Phloretin is a well-known inhibitor of eukaryotic urea transporters, blocks VacA-mediated urea and ion transport.
  • Description
    Phloretin is a well-known inhibitor of eukaryotic urea transporters, blocks VacA-mediated urea and ion transport. Phloretin is a dihydrochalcone, a type of natural phenols. It can be found in apple tree leaves and the Manchurian apricot. It promotes potent antioxidative activities in peroxynitrite scavenging and the inhibition of lipid peroxidation. It has been found to inhibit the growth of several cancer cells and induce apoptosis of B16 melanoma and HL60 human leukemia cells.
  • Synonyms
    NSC 407292; RJC 02792
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    SGLT1; SGLT2
  • Research Area
    Metabolic Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    60-82-2
  • Formula Weight
    274.28
  • Molecular Formula
    C15H14O5
  • Purity
    98%
  • Solubility
    DMSO : 50 mg/mL 182.30 mM; H2O : < 0.1 mg/mL
  • SMILES
    c1(c(c(cc(c1)O)O)C(=O)CCc1ccc(cc1)O)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Chan SS, et al. Am J Physiol, 1962, 203, 975-979.
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