Phloretin

Research use only, not for human use.

Phloretin is a well-known inhibitor of eukaryotic urea transporters, blocks VacA-mediated urea and ion transport.

Phloretin is a well-known inhibitor of eukaryotic urea transporters, blocks VacA-mediated urea and ion transport. Phloretin is a dihydrochalcone, a type of natural phenols. It can be found in apple tree leaves and the Manchurian apricot. It promotes potent antioxidative activities in peroxynitrite scavenging and the inhibition of lipid peroxidation. It has been found to inhibit the growth of several cancer cells and induce apoptosis of B16 melanoma and HL60 human leukemia cells.

NSC 407292; RJC 02792

Others

Other Targets

SGLT1; SGLT2

Metabolic Disease

——

60-82-2

274.28

C15H14O5

98%

DMSO : 50 mg/mL 182.30 mM; H2O : < 0.1 mg/mL

c1(c(c(cc(c1)O)O)C(=O)CCc1ccc(cc1)O)O

——

(-20℃)

With Ice Pack

≥ 2 years