Amifloxacin

CAS No. 86393-37-5

Amifloxacin ( Win49375 )

Catalog No. M26863 CAS No. 86393-37-5

Amifloxacin is a synthetic antibacterial compound and showed moderate activity against Staphylococcus aureus, with MICs of less than or equal to 2 micrograms/ml.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Amifloxacin
  • Note
    Research use only, not for human use.
  • Brief Description
    Amifloxacin is a synthetic antibacterial compound and showed moderate activity against Staphylococcus aureus, with MICs of less than or equal to 2 micrograms/ml.
  • Description
    Amifloxacin is a synthetic antibacterial compound and showed moderate activity against Staphylococcus aureus, with MICs of less than or equal to 2 micrograms/ml.(In Vitro):The activity of Amifloxacin in vitro was comparable to those of norfloxacin and pefloxacin against Enterobacteriaceae and generally greater than those of tobramycin and cefotaxime. Amifloxacin was more active in vitro than carbenicillin and mezlocillin against Pseudomonas aeruginosa isolates.(In Vivo):Against systemic, gram-negative bacterial infections in mice, Amifloxacin was generally less active than cefotaxime but more active than gentamicin. WIN 49548, the major piperazinyl-N-desmethyl metabolite of Amifloxacin, was aa effective as the parent drug against experimental infections in mice when given parenterally. When administered orally, however, this metabolite was less potent than Amifloxacin. Amifloxacin was highly active by the oral route, with 50% effective doses within two- to threefold of those obtained with parenteral medication.
  • Synonyms
    Win49375
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Nucleoside Antimetabolite/Analog
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    86393-37-5
  • Formula Weight
    334.4
  • Molecular Formula
    C16H19FN4O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CNn1cc(C(O)=O)c(=O)c2cc(F)c(cc12)N1CCN(C)CC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kurtzberg J. Guanine arabinoside as a bone marrow-purging agent. Ann N Y Acad Sci. 1993 Jun 23;685:225-36.
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