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Amcinonide

CAS No. 51022-69-6

Amcinonide( CL 34,699 )

Catalog No. M14754 CAS No. 51022-69-6

Amcinonide inhibit NO release from activated microglia with IC50 3.38 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Amcinonide
  • Note
    Research use only, not for human use.
  • Brief Description
    Amcinonide inhibit NO release from activated microglia with IC50 3.38 nM.
  • Description
    Amcinonide inhibit NO release from activated microglia with IC50 3.38 nM. Amcinonide has affinity for the glucocorticoid receptor.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    CL 34,699
  • Pathway
    Endocrinology/Hormones
  • Target
    Annexin A
  • Recptor
    Annexin A1| Glucocorticoid Receptor
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    51022-69-6
  • Formula Weight
    502.57
  • Molecular Formula
    C28H35FO7
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 10 mM
  • SMILES
    CC(OCC(C([C@@](O1)([H])C[C@@]2([H])C3CCC4=CC5=O)(C2(C)CC(O)C3(F)C4(C)C=C5)OC61CCCC6)=O)=O
  • Chemical Name
    2-((11a'R,12a'S)-6b'-fluoro-7'-hydroxy-6a',8a'-dimethyl-4'-oxo-1',2',4',6a',6b',7',8',8a',11a',12',12a',12b'-dodecahydro-8b'H-spiro[cyclopentane-1,10'-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxole]-8b'-yl)-2-oxoethyl acetate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Grossman R, et al. Ann N Y Acad Sci. 2006 Jul;1071:410-2
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