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Alacepril

CAS No. 74258-86-9

Alacepril( Cetapril | DU-1219 )

Catalog No. M21079 CAS No. 74258-86-9

Alacepril is a relatively novel angiotensin-converting enzyme inhibitor used as an antihypertensive.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Alacepril
  • Note
    Research use only, not for human use.
  • Brief Description
    Alacepril is a relatively novel angiotensin-converting enzyme inhibitor used as an antihypertensive.
  • Description
    Alacepril is a relatively novel angiotensin-converting enzyme inhibitor used as an antihypertensive.(In Vivo):The long lasting antihypertensive effect of Alacepril in renal hypertensive rats is confirmed by once daily successive oral administration (1-2 mg/kg/d). In renal hypertensive dogs, Alacepril (3 mg/kg) showed a stable and sustained hypotensive effect, and its duration of action was longer than that of captopril.
  • In Vitro
    ——
  • In Vivo
    The long lasting antihypertensive effect of Alacepril in renal hypertensive rats is confirmed by once daily successive oral administration (1-2 mg/kg/d). In renal hypertensive dogs, Alacepril (3 mg/kg) showed a stable and sustained hypotensive effect, and its duration of action was longer than that of captopril.
  • Synonyms
    Cetapril | DU-1219
  • Pathway
    Endocrinology/Hormones
  • Target
    RAAS
  • Recptor
    Angiotensin Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    74258-86-9
  • Formula Weight
    406.5
  • Molecular Formula
    C20H26N2O5S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (246.00 mM)
  • SMILES
    CC(=O)SCC(C)C(=O)N1CCCC1C(=O)NC(Cc1ccccc1)C(=O)O
  • Chemical Name
    (3-(acetylthio)-2-methylpropanoyl)-L-prolyl-L-phenylalanine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kinugawa T Osaki S Kato M et al. Effects of the angiotensin-converting enzyme inhibitor alacepril on exercise capacity and neurohormonal factors in patients with mild-to-moderate heart failure[J]. Clin Exp Pharmacol Physiol 2002 29(12):1060-1065.
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