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L162389
CAS No. 169281-53-2
L162389( —— )
Catalog No. M32992 CAS No. 169281-53-2
L162389 is an orally active and potent angiotensin II receptor antagonist with a balanced affinity for AT1 and AT2 receptor subtypes that stimulates the conversion of phosphatidylinositol.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 751 | In Stock |
|
| 10MG | 1064 | In Stock |
|
| 25MG | 1587 | In Stock |
|
| 50MG | 2027 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameL162389
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NoteResearch use only, not for human use.
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Brief DescriptionL162389 is an orally active and potent angiotensin II receptor antagonist with a balanced affinity for AT1 and AT2 receptor subtypes that stimulates the conversion of phosphatidylinositol.
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DescriptionL162389 is a potent antagonist of angiotensin AT1 receptor with Ki of 28 nM.
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In VitroL-162,389 stimulates phosphatidylinositol turnover, albeit only to a small percentage of the angiotensin response. L-162,389 acts as angiotensin antagonist with IC50 value of 105 nM.
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In Vivo——
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetRAAS
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RecptorRAAS
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Research Area——
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Indication——
Chemical Information
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CAS Number169281-53-2
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Formula Weight562.72
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Molecular FormulaC31H38N4O4S
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(OCCCC)NS(=O)(=O)C=1C=CC(=CC1C2=CC=C(C=C2)CN3C4=NC(=CC(=C4N=C3CC)C)C)CCC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Perlman S, et al. Dual agonistic and antagonistic property of nonpeptide angiotensin AT1 ligands: susceptibility to receptor mutations. Mol Pharmacol. 1997 Feb;51(2):301-11.?
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