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Acetamiprid

CAS No. 135410-20-7

Acetamiprid ( —— )

Catalog No. M22564 CAS No. 135410-20-7

Acetamiprid is a nicotinic acetylcholine receptor (nAChR) agonist. Acetamiprid is a neonicotinoid insecticide used worldwide. It is shown to be associated with neuromuscular and reproductive disorders. Acetamiprid decreases in body weight and mildly affected spermatogenesis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Acetamiprid
  • Note
    Research use only, not for human use.
  • Brief Description
    Acetamiprid is a nicotinic acetylcholine receptor (nAChR) agonist. Acetamiprid is a neonicotinoid insecticide used worldwide. It is shown to be associated with neuromuscular and reproductive disorders. Acetamiprid decreases in body weight and mildly affected spermatogenesis.
  • Description
    Acetamiprid is a nicotinic acetylcholine receptor (nAChR) agonist. Acetamiprid is a neonicotinoid insecticide used worldwide. It is shown to be associated with neuromuscular and reproductive disorders. Acetamiprid decreases in body weight and mildly affected spermatogenesis. Acetamiprid disrupts subsequent testosterone biosynthesis by decreasing the rate of conversion of cholesterol to testosterone and by preventing cholesterol from entering the mitochondria within the Leydig cells. These effects caused reproductive damage to the rats. Acetamiprid decreases the expression of testosterone-metabolism genes, nAChR subunit genes, and proliferation-associated genes in mice.
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    AChR
  • Recptor
    nAChR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    135410-20-7
  • Formula Weight
    222.67
  • Molecular Formula
    C10H11ClN4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:97 mg/mL (435.62mM)
  • SMILES
    CN(Cc1ccc(Cl)nc1)C(C)=NC#N
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Terayama H, et al. Effect of acetamiprid on the immature murine testes. Int J Environ Health Res. 2018 Dec;28(6):683-696.
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