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Ac-IETD-pNA
CAS No. 219138-21-3
Ac-IETD-pNA( ——— )
Catalog No. M41648 CAS No. 219138-21-3
Ac-Ile-Glu-Thr-Asp-pNA is a substrate for caspase-8.Caspase-8 binds to and cleaves the Ile-Glu-Thr-Asp (IETD) peptide sequence to release p-nitroalinide, which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 200 | In Stock |
|
| 10MG | 314 | In Stock |
|
| 25MG | Get Quote | In Stock |
|
| 50MG | Get Quote | In Stock |
|
| 100MG | Get Quote | In Stock |
|
Biological Information
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Product NameAc-IETD-pNA
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NoteResearch use only, not for human use.
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Brief DescriptionAc-Ile-Glu-Thr-Asp-pNA is a substrate for caspase-8.Caspase-8 binds to and cleaves the Ile-Glu-Thr-Asp (IETD) peptide sequence to release p-nitroalinide, which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity.
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DescriptionAc-Ile-Glu-Thr-Asp-pNA is a substrate for caspase-8.Caspase-8 binds to and cleaves the Ile-Glu-Thr-Asp (IETD) peptide sequence to release p-nitroalinide, which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity.
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In Vitro———
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In Vivo———
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Synonyms———
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PathwayOthers
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TargetOther Targets
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Recptor———
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Research Area———
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Indication———
Chemical Information
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CAS Number219138-21-3
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Formula Weight638.6
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Molecular FormulaC27H38N6O12
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Purity>98% (HPLC)
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SolubilityH2O : 0.98 mg/mL (1.53 mM; adjust pH to 12 with 1 M NaOH)
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SMILES———
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Smith GK, et al. Expression, preparation, and high-throughput screening of caspase-8: discovery of redox-based and steroid diacid inhibition. Arch Biochem Biophys. 2002;399(2):195-205.?
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