Ac-Arg-OH

CAS No. 155-84-0

Ac-Arg-OH ( —— )

Catalog No. M21398 CAS No. 155-84-0

N-a-Acetyl-L-arginine also known as N-ac-L-arg-OH or N-alpha-acetylarginine belongs to the class of organic compounds known as n-acyl-l-alpha-amino acids.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Ac-Arg-OH
  • Note
    Research use only not for human use.
  • Brief Description
    N-a-Acetyl-L-arginine also known as N-ac-L-arg-OH or N-alpha-acetylarginine belongs to the class of organic compounds known as n-acyl-l-alpha-amino acids.
  • Description
    N-a-Acetyl-L-arginine also known as N-ac-L-arg-OH or N-alpha-acetylarginine belongs to the class of organic compounds known as n-acyl-l-alpha-amino acids. These are n-acylated alpha amino acids which have the L-configuration of the alpha-carbon atom. N-a-Acetyl-L-arginine serum levels (and other guanidino compounds) were elevated of all the hyperargininemic patients are higher than the normal range. N-a-Acetyl-L-arginine is a very strong basic compound (based on its pKa). Untreated hyperargininemic patients have the highest guanidino compound levels in cerebrospinal fluid. N-a-Acetyl-L-arginine is one of the guanidino compounds found elevated in the serum of an hemodialyzed renal insufficient (uremic) pediatric population. Outside of the human body N-a-Acetyl-L-arginine has been detected but not quantified in apples and loquats. This could make N-a-acetyl-L-arginine a potential biomarker for the consumption of these foods. N-a-Acetyl-L-arginine with regard to humans has been found to be associated with several diseases such as uremia and colorectal cancer; N-a-acetyl-L-arginine has also been linked to the inborn metabolic disorder hyperargininemia. During a low-arginine diet together with sodium benzoate therapy there was a marked decrease in plasma N-alpha-acetylarginine. N-a-Acetyl-L-arginine increases in urine hyperargininemic patients.
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Human Endogenous Metabolite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    155-84-0
  • Formula Weight
    216.24
  • Molecular Formula
    C8H16N4O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:43 mg/mL (198.85 mM)
  • SMILES
    CC(N[C@@H](CCCNC(N)=N)C(O)=O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.De Deyn PP et al. Serum guanidino compound levels in uremic pediatric patients treated with hemodialysis or continuous cycle peritoneal dialysis. Correlations between nerve conduction velocities and altered guanidino compound concentrations. Nephron. 1995;69(4):411-7.
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