Absinthiin

Research use only, not for human use.

Absinthiin is a weak HIV-1 protease inhibitor.

Absinthin is possible treatment candidate for Acute lung injury (ALI). ALI symptoms include severe lung inflammation. Absinthin causes an anti-inflammatory effect by enhancing activity of matrix metalloproteinase-8 (MMP-8), which inhibits grwoth of inflammatory cells.

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Animal Model:LPS-induced acute lung injury in miceDosage:20, 40, 80mg/kg Administration:p.o.Result:Reduced inflammatory cell infiltration and improved lung architecture.Reduced MPO activity, infiltration of neutrophils, lung tissue wet-to-dry ratio.Reduced the secretion of proinflammatory cytokines and chemokines (TNF-α, IL-1β, IL-6, and MIP-1α).

Absinthin | NSC 407315 | NSC-407315

Others

Other Targets

HIV-1 protease

Others-Field

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1362-42-1

496.64

C30H40O6

>98% (HPLC)

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CC1C2CCC(C3C4C5C=C(C6(C4C(=C3C2OC1=O)C)C5C(CCC7C6OC(=O)C7C)(C)O)C)(C)O

[no name]

(-20℃)

With Ice Pack

≥ 2 years