Abbolactone( SC9420 | SC-9420 | Spironolactone | Spiresis )

Catalog No. M17714 CAS No. 52-01-7

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

Abbolactone
Note

Research use only, not for human use.
Brief Description

Spironolactone is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.
Description

Spironolactone is a medication primarily used to treat fluid build-up due to heart failure, liver scarring, or kidney disease. Other uses include high blood pressure, low blood potassium that does not improve with supplementation, early puberty, excessive hair growth in women, and as a component of hormone replacement therapy for trans women.
In Vitro

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In Vivo

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Synonyms

SC9420 | SC-9420 | Spironolactone | Spiresis
Pathway

Metabolic Enzyme/Protease
Target

Phospholipase
Recptor

Androgen Receptor
Research Area

Metabolic Disease
Indication

——

CAS Number

52-01-7
Formula Weight

416.57
Molecular Formula

C24H32O4S
Purity

>98% (HPLC)
Solubility

DMSO : ≥ 50 mg/mL 120.03 mM; H2O : < 0.1 mg/mL
SMILES

CC(=O)S[C@@H]1CC2=CC(=O)CC[C@@]2([C@@H]3[C@@H]1[C@@H]4CC[C@]5([C@]4(CC3)C)CCC(=O)O5)C
Chemical Name

S-((7R,8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-yl) ethanethioate

1. Ye P, et al. Horm Metab Res. 2009 Jan;41(1):35-9.

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