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AZD6280

CAS No. 942436-93-3

AZD6280( AZD 6280 )

Catalog No. M16744 CAS No. 942436-93-3

AZD6280 is a potent, α2/3 functionally selective, partial GABAA receptor modulator with pKi of 7.7.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    AZD6280
  • Note
    Research use only, not for human use.
  • Brief Description
    AZD6280 is a potent, α2/3 functionally selective, partial GABAA receptor modulator with pKi of 7.7.
  • Description
    AZD6280 is a potent, α2/3 functionally selective, partial GABAA receptor modulator with pKi of 7.7; exerts neutral antagonism at the α1-subunit and partial efficacy at the α2,3-subunits over the α5-subunit, shows potential for the treatment of anxiety disorders.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    AZD 6280
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    GAT
  • Recptor
    GAT
  • Research Area
    Neurological Disease
  • Indication
    Anxiety

Chemical Information

  • CAS Number
    942436-93-3
  • Formula Weight
    366.421
  • Molecular Formula
    C20H22N4O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 62.5 mg/mL (170.57 mM)
  • SMILES
    CCCNC(=O)c1c(c2cccc(c2nn1)c3cc(ccc3OC)OC)N
  • Chemical Name
    4-amino-8-(2,5-dimethoxyphenyl)-N-propyl-3-cinnolinecarboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Jucaite A, et al. Psychopharmacology (Berl). 2017 Feb;234(4):707-716. 2. Chen X, et al. J Clin Psychopharmacol. 2015 Feb;35(1):22-33. 3. Te Beek ET, et al. Clin Pharmacol Drug Dev. 2015 Mar;4(2):149-54.
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