AZD6280( AZD 6280 )

Catalog No. M16744 CAS No. 942436-93-3

AZD6280 is a potent, α2/3 functionally selective, partial GABAA receptor modulator with pKi of 7.7.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	510	In Stock
5MG	464	In Stock
10MG	676	In Stock
25MG	1074	In Stock
50MG	1469	In Stock
100MG	2000	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

AZD6280
Note

Research use only, not for human use.
Brief Description

AZD6280 is a potent, α2/3 functionally selective, partial GABAA receptor modulator with pKi of 7.7.
Description

AZD6280 is a potent, α2/3 functionally selective, partial GABAA receptor modulator with pKi of 7.7; exerts neutral antagonism at the α1-subunit and partial efficacy at the α2,3-subunits over the α5-subunit, shows potential for the treatment of anxiety disorders.
In Vitro

——
In Vivo

——
Synonyms

AZD 6280
Pathway

Membrane Transporter/Ion Channel
Target

GAT
Recptor

GAT
Research Area

Neurological Disease
Indication

Anxiety

Chemical Information

CAS Number

942436-93-3
Formula Weight

366.421
Molecular Formula

C20H22N4O3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 62.5 mg/mL (170.57 mM)
SMILES

CCCNC(=O)c1c(c2cccc(c2nn1)c3cc(ccc3OC)OC)N
Chemical Name

4-amino-8-(2,5-dimethoxyphenyl)-N-propyl-3-cinnolinecarboxamide

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Jucaite A, et al. Psychopharmacology (Berl). 2017 Feb;234(4):707-716. 2. Chen X, et al. J Clin Psychopharmacol. 2015 Feb;35(1):22-33. 3. Te Beek ET, et al. Clin Pharmacol Drug Dev. 2015 Mar;4(2):149-54.

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