AZD5423
CAS No. 1034148-04-3
AZD5423 ( —— )
Catalog No. M23241 CAS No. 1034148-04-3
AZD5423 is an inhaled, potent, selective, and non-steroidal modulator of glucocorticoid receptor (GR) and it effectively reduces allergen-induced responses in subjects with mild allergic asthma.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 53 | In Stock |
|
5MG | 87 | In Stock |
|
10MG | 147 | In Stock |
|
25MG | 267 | In Stock |
|
50MG | 475 | In Stock |
|
100MG | 692 | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameAZD5423
-
NoteResearch use only, not for human use.
-
Brief DescriptionAZD5423 is an inhaled, potent, selective, and non-steroidal modulator of glucocorticoid receptor (GR) and it effectively reduces allergen-induced responses in subjects with mild allergic asthma.
-
DescriptionAZD5423 is an inhaled, potent, selective, and non-steroidal modulator of glucocorticoid receptor (GR) and it effectively reduces allergen-induced responses in subjects with mild allergic asthma.
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorGlucocorticoid receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1034148-04-3
-
Formula Weight487.5
-
Molecular FormulaC25H21F4N3O3
-
Purity>98% (HPLC)
-
SolubilityDMSO:100 mg/mL (205.15 mM; Need ultrasonic)
-
SMILESO=C(N[C@@H](C)[C@H](OC1=CC2=C(N(C3=CC=C(F)C=C3)N=C2)C=C1)C4=CC=CC(OC)=C4)C(F)(F)F
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Werkstr?m V, et al. Safety, Pharmacokinetics and Pharmacodynamics of the Selective Glucocorticoid Receptor Modulator AZD5423 after Inhalation in Healthy Volunteers. Basic Clin Pharmacol Toxicol. 2016 Dec;119(6):574-581.
molnova catalog
related products
-
PMEDAP
PMEDAP is a potent inhibitor of Moloney murine sarcoma virus (MSV)-induced tumor formation and associated mortality and an inhibitor of human immunodeficiency virus (HIV) replication. PMEDAP also has anti-murine cytomegalovirus (MCMV) activity.
-
3-Phenylpropyl isoth...
3-Phenylpropyl isothiocyanate has a stronger inhibitory effect on N-nitrosomethyl-benzylamine (NMBA) tumorigenesis. 3-Phenylpropyl isothiocyanate has chemopreventive effects.
-
Enmein, 13-deoxy-19-...
Enmein, 13-deoxy-19-hydroxy-, (19R)- is an Enmein-?type diterpene derivative and can be used in the preparation of antitumor drugs.