AZD5423

CAS No. 1034148-04-3

AZD5423 ( —— )

Catalog No. M23241 CAS No. 1034148-04-3

AZD5423 is an inhaled, potent, selective, and non-steroidal modulator of glucocorticoid receptor (GR) and it effectively reduces allergen-induced responses in subjects with mild allergic asthma.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 53 In Stock
5MG 87 In Stock
10MG 147 In Stock
25MG 267 In Stock
50MG 475 In Stock
100MG 692 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    AZD5423
  • Note
    Research use only, not for human use.
  • Brief Description
    AZD5423 is an inhaled, potent, selective, and non-steroidal modulator of glucocorticoid receptor (GR) and it effectively reduces allergen-induced responses in subjects with mild allergic asthma.
  • Description
    AZD5423 is an inhaled, potent, selective, and non-steroidal modulator of glucocorticoid receptor (GR) and it effectively reduces allergen-induced responses in subjects with mild allergic asthma.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Glucocorticoid receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1034148-04-3
  • Formula Weight
    487.5
  • Molecular Formula
    C25H21F4N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:100 mg/mL (205.15 mM; Need ultrasonic)
  • SMILES
    O=C(N[C@@H](C)[C@H](OC1=CC2=C(N(C3=CC=C(F)C=C3)N=C2)C=C1)C4=CC=CC(OC)=C4)C(F)(F)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Werkstr?m V, et al. Safety, Pharmacokinetics and Pharmacodynamics of the Selective Glucocorticoid Receptor Modulator AZD5423 after Inhalation in Healthy Volunteers. Basic Clin Pharmacol Toxicol. 2016 Dec;119(6):574-581.
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