Cart
sales@molnova.com
AZD5305
CAS No. 2589531-76-8
AZD5305( —— )
Catalog No. M24160 CAS No. 2589531-76-8
AZD5305 is a potent, selective and oral active PARP inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 222 | In Stock |
|
| 10MG | 357 | In Stock |
|
| 25MG | 597 | In Stock |
|
| 50MG | 851 | In Stock |
|
| 100MG | 1152 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameAZD5305
-
NoteResearch use only, not for human use.
-
Brief DescriptionAZD5305 is a potent, selective and oral active PARP inhibitor.
-
DescriptionAZD5305 is a potent, selective and oral active PARP inhibitor.
-
In Vitro——
-
In VivoAnimal Model:Female Han Wistar rats with BRCAm xenograft and PDX models (12-13 weeks of age)Dosage:0.01, 0.03, 0.1, and 0.3 mg/kg Administration:Oral administration; daily, for 35 days Result:Had antitumor efficacy in a dose-dependent manner.
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetPARP
-
RecptorPARP
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2589531-76-8
-
Formula Weight406.48
-
Molecular FormulaC22H26N6O2
-
Purity>98% (HPLC)
-
SolubilityDMSO:41.67 mg/mL (102.51 mM; Need ultrasonic)
-
SMILESO=C(C1=NC=C(N2CCN(CC3=CC(N4)=C(N=C3)C=C(CC)C4=O)CC2)C=C1)NC
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
molnova catalog
related products
-
Perospirone
Perospirone is an antagonist of serotonin 5HT2A receptors and dopamine D2 receptors. It also displays affinity towards 5HT1A receptors as a partial agonist.
-
WAY-620473
WAY-620473 is a potent PARP-1 inhibitor with antitumor activity and alters eukaryotic lifespan.
-
Rucaparib Camsylate
Rucaparib Camsylate is a PARP inhibitor (PARP1,Ki of 1.4 nM). Rucaparib Camsylate also displays binding affinity to eight other PARP domains. Rucaparib is the most effective PARP inhibitor in enzyme assays (Ki: 1.4 nM). Rucaparib inhibits PARP-1 activity by 97.1% at a concentration of 1 μM in permeabilized D283Med cells.
