AZD-9819( AZD9819 )

Catalog No. M16832 CAS No. 956907-23-6

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

AZD-9819
Note

Research use only, not for human use.
Brief Description

AZD-9819 is an inhibitor of human neutrophil elastase for potential treatment of chronic obstructive pulmonary disease.
Description

AZD-9819 is an inhibitor of human neutrophil elastase for potential treatment of chronic obstructive pulmonary disease.COPD Phase 1 Discontinued.
In Vitro

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In Vivo

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Synonyms

AZD9819
Pathway

Metabolic Enzyme/Protease
Target

Elastase
Recptor

Elastase
Research Area

Inflammation/Immunology
Indication

COPD

CAS Number

956907-23-6
Formula Weight

492.462
Molecular Formula

C25H19F3N6O2
Purity

>98% (HPLC)
Solubility

——
SMILES

CCNC(=O)C1=NC(=C(C)N(C1=O)c2cccc(c2)C(F)(F)F)c3ccnn3c4ccc(cc4)C#N
Chemical Name

6-(1-(4-cyanophenyl)-1H-pyrazol-5-yl)-N-ethyl-5-methyl-3-oxo-4-(3-(trifluoromethyl)phenyl)-3,4-dihydropyrazine-2-carboxamide

1. Gu C, et al. Drug Metab Dispos. 2015 Oct;43(10):1441-9.

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