Cart
sales@molnova.com
AZD-0837
CAS No. 433937-93-0
AZD-0837( AZD0837 | Atecegatran metoxil )
Catalog No. M14477 CAS No. 433937-93-0
AZD-0837 is a novel oral anticoagulant that after bioconversion to its active form is a potent and reversible thrombin inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1053 | Get Quote |
|
| 50MG | 2142 | Get Quote |
|
| 100MG | 2790 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameAZD-0837
-
NoteResearch use only, not for human use.
-
Brief DescriptionAZD-0837 is a novel oral anticoagulant that after bioconversion to its active form is a potent and reversible thrombin inhibitor.
-
DescriptionAZD-0837 is a novel oral anticoagulant that after bioconversion to its active form is a potent and reversible thrombin inhibitor, has been investigated in phase II studies for prevention of stroke and systemic embolic events in patients with atrial fibrillation (AF).Thrombosis Phase 2 Discontinued.
-
In Vitro——
-
In Vivo——
-
SynonymsAZD0837 | Atecegatran metoxil
-
PathwayAutophagy
-
TargetThrombin
-
RecptorThrombin
-
Research AreaCardiovascular Disease
-
IndicationThrombosis
Chemical Information
-
CAS Number433937-93-0
-
Formula Weight496.896
-
Molecular FormulaC22H23ClF2N4O5
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C([C@H]1N(C([C@@H](C2=CC(OC(F)F)=CC(Cl)=C2)O)=O)CC1)NCC3=CC=C(C(NOC)=N)C=C3
-
Chemical Name(S)-1-((R)-2-(3-chloro-5-(difluoromethoxy)phenyl)-2-hydroxyacetyl)-N-(4-(N-methoxycarbamimidoyl)benzyl)azetidine-2-carboxamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Schützer KM, et al. Eur J Clin Pharmacol. 2010 Sep;66(9):903-10.
2. Lip GY, et al. Thromb Res. 2011 Feb;127(2):91-9.
3. Matsson EM, et al. Mol Pharm. 2013 Nov 4;10(11):4252-62.
4. Deinum J, et al. Thromb Haemost. 2009 Jun;101(6):1051-9.
molnova catalog
related products
-
Etamsylate
Ethamsylate is a haemostatic drug, which inhibits biosynthesis and action of prostaglandins, and increases capillary endothelial resistance as and platelet adhesion.
-
NP-313
NP-313 (NSC-4264) is a potent antithrombotic agent that inhibits platelet aggregation and activation by inhibiting thromboxane A 2 synthesis and selectively inhibiting SOCC-mediated Ca2+ efflux.
-
Argatroban
Argatroban is a direct, selective thrombin inhibitor.
