Cart
sales@molnova.com
Home - Products - Autophagy - Thrombin - AZD-0837

AZD-0837

CAS No. 433937-93-0

AZD-0837( AZD0837 | Atecegatran metoxil )

Catalog No. M14477 CAS No. 433937-93-0

AZD-0837 is a novel oral anticoagulant that after bioconversion to its active form is a potent and reversible thrombin inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 1053 Get Quote
50MG 2142 Get Quote
100MG 2790 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    AZD-0837
  • Note
    Research use only, not for human use.
  • Brief Description
    AZD-0837 is a novel oral anticoagulant that after bioconversion to its active form is a potent and reversible thrombin inhibitor.
  • Description
    AZD-0837 is a novel oral anticoagulant that after bioconversion to its active form is a potent and reversible thrombin inhibitor, has been investigated in phase II studies for prevention of stroke and systemic embolic events in patients with atrial fibrillation (AF).Thrombosis Phase 2 Discontinued.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    AZD0837 | Atecegatran metoxil
  • Pathway
    Autophagy
  • Target
    Thrombin
  • Recptor
    Thrombin
  • Research Area
    Cardiovascular Disease
  • Indication
    Thrombosis

Chemical Information

  • CAS Number
    433937-93-0
  • Formula Weight
    496.896
  • Molecular Formula
    C22H23ClF2N4O5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C([C@H]1N(C([C@@H](C2=CC(OC(F)F)=CC(Cl)=C2)O)=O)CC1)NCC3=CC=C(C(NOC)=N)C=C3
  • Chemical Name
    (S)-1-((R)-2-(3-chloro-5-(difluoromethoxy)phenyl)-2-hydroxyacetyl)-N-(4-(N-methoxycarbamimidoyl)benzyl)azetidine-2-carboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Schützer KM, et al. Eur J Clin Pharmacol. 2010 Sep;66(9):903-10. 2. Lip GY, et al. Thromb Res. 2011 Feb;127(2):91-9. 3. Matsson EM, et al. Mol Pharm. 2013 Nov 4;10(11):4252-62. 4. Deinum J, et al. Thromb Haemost. 2009 Jun;101(6):1051-9.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Enoxaparin sodium

    Enoxaparin sodium is a low-molecular-weight heparin (LMWH) that has recently been approved by the US FDA for use in patients with medically managed ST-segment myocardial infarction (STEMI), or STEMI with subsequent percutaneous coronary intervention (PCI).

  • Pirodomast

    Pirodomast is a thromboxane A (TXA2) synthase inhibitor.

  • Argatroban

    Argatroban is a direct, selective thrombin inhibitor.

Sign In Join Free