AUTEN-99

CAS No. 904054-02-0

AUTEN-99 ( —— )

Catalog No. M16499 CAS No. 904054-02-0

A small molecule autophagy enhancer that inhibit the myotubularin-related phosphatase MTMR14/Jumpy.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    AUTEN-99
  • Note
    Research use only, not for human use.
  • Brief Description
    A small molecule autophagy enhancer that inhibit the myotubularin-related phosphatase MTMR14/Jumpy.
  • Description
    A small molecule autophagy enhancer that inhibit the myotubularin-related phosphatase MTMR14/Jumpy; induces autophagic flux and promotes cell survival in mammalian cell cultures; increases the number of autophagic structures in mice and Drosophila, and effectively penetrates through a blood-brain barrier model; impedes the progression of neurodegenerative symptoms in Drosophila models of Parkinson's and Huntington's diseases.
  • Synonyms
    ——
  • Pathway
    Autophagy
  • Target
    Autophagy
  • Recptor
    Autophagy
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    904054-02-0
  • Formula Weight
    278.37
  • Molecular Formula
    C17H14N2S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    2-([1,1'-biphenyl]-4-yl)-5,6-dihydroimidazo[2,1-b]thiazole

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kovács T, et al. Sci Rep. 2017 Feb 16;7:42014.
molnova catalog
related products
  • LC3-mHTT-IN-AN1

    LC3-mHTT-IN-AN1 (Compound AN1) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN1 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.

  • SR-3677

    SR-3677 is an effective and specific inhibitor of ROCK2 (IC50: 3 nM).

  • IITZ-01

    IITZ-01 (Autophagy inhibitor IITZ-01) is a novel potent lysosomotropic autophagy inhibitor.