Graveoline

CAS No. 485-61-0

Graveoline( 2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one | Foliosine )

Catalog No. M24439 CAS No. 485-61-0

Graveoline is an apoptosis and autophagy inducer in skin melanoma cancer cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Graveoline
  • Note
    Research use only, not for human use.
  • Brief Description
    Graveoline is an apoptosis and autophagy inducer in skin melanoma cancer cells.
  • Description
    Graveoline is an apoptosis and autophagy inducer in skin melanoma cancer cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one | Foliosine
  • Pathway
    Autophagy
  • Target
    Autophagy
  • Recptor
    autophagy
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    485-61-0
  • Formula Weight
    279.29
  • Molecular Formula
    C17H13NO3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    CN1C2=CC=CC=C2C(=O)C=C1C3=CC4=C(C=C3)OCO4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ghosh S, Bishayee K, Khuda-Bukhsh AR. Graveoline isolated from ethanolic extract of Ruta graveolens triggers apoptosis and autophagy in skin melanoma cells: a novel apoptosis-independent autophagic signaling pathway. Phytother Res. 2014;28(8):1153-1162. doi:10.1002/ptr.5107
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