AS101

CAS No. 106566-58-9

AS101 ( AS-101; IVX-Q-101; PRX-0001 )

Catalog No. M17134 CAS No. 106566-58-9

AS101, a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 71 In Stock
10MG 110 In Stock
25MG 173 In Stock
50MG 264 In Stock
100MG 397 In Stock
200MG 584 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    AS101
  • Note
    Research use only, not for human use.
  • Brief Description
    AS101, a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.
  • Description
    AS101, also known as Ossirene, is a synthetic non-toxic tellurium derivative, structurally similar to cisplatin, with immuno-modulating, antiviral, and hair growth-promoting activities. Ammonium trichlorotellurate may inhibit the inflammatory cytokine interleukin-10 (IL-10) and may induce hematopoietic cells to express interleukin-2 (IL-2), IL-2 receptors, granulocyte-macrophage colony-stimulating factor (GM-CSF), IL-3, tumor necrosis factor (TNF) and interferons (INFs). This agent is also a potent inducer of IL-1 and IL-6. Accordingly, ammonium trichlorotellurate may protect against chemotherapy-induced myelosuppression. In addition, this agent exhibits hair growth-promoting activity by inducing anagen production and inhibiting catagen production, resulting in the promotion of follicular keratinocyte proliferation and interference with follicular keratinocyte terminal differentiation, respectively. Accordingly, ammonium trichlorotellurate may protect against chemotherapy-induced alopecia.
  • Synonyms
    AS-101; IVX-Q-101; PRX-0001
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    IL-1β converting enzyme
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    106566-58-9
  • Formula Weight
    312.05
  • Molecular Formula
    C2H4Cl3O2Te·H4N
  • Purity
    98%
  • Solubility
    ——
  • SMILES
    C1CO[Te](O1)(Cl)(Cl)Cl.[NH4+]
  • Chemical Name
    Ammonium trichloro(dioxoethylene-O,O') tellurate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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