AS101
CAS No. 106566-58-9
AS101 ( AS-101; IVX-Q-101; PRX-0001 )
Catalog No. M17134 CAS No. 106566-58-9
AS101, a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 71 | In Stock |
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10MG | 110 | In Stock |
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25MG | 173 | In Stock |
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50MG | 264 | In Stock |
|
100MG | 397 | In Stock |
|
200MG | 584 | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
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Biological Information
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Product NameAS101
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NoteResearch use only, not for human use.
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Brief DescriptionAS101, a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.
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DescriptionAS101, also known as Ossirene, is a synthetic non-toxic tellurium derivative, structurally similar to cisplatin, with immuno-modulating, antiviral, and hair growth-promoting activities. Ammonium trichlorotellurate may inhibit the inflammatory cytokine interleukin-10 (IL-10) and may induce hematopoietic cells to express interleukin-2 (IL-2), IL-2 receptors, granulocyte-macrophage colony-stimulating factor (GM-CSF), IL-3, tumor necrosis factor (TNF) and interferons (INFs). This agent is also a potent inducer of IL-1 and IL-6. Accordingly, ammonium trichlorotellurate may protect against chemotherapy-induced myelosuppression. In addition, this agent exhibits hair growth-promoting activity by inducing anagen production and inhibiting catagen production, resulting in the promotion of follicular keratinocyte proliferation and interference with follicular keratinocyte terminal differentiation, respectively. Accordingly, ammonium trichlorotellurate may protect against chemotherapy-induced alopecia.
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SynonymsAS-101; IVX-Q-101; PRX-0001
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PathwayOthers
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TargetOther Targets
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RecptorIL-1β converting enzyme
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number106566-58-9
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Formula Weight312.05
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Molecular FormulaC2H4Cl3O2Te·H4N
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Purity98%
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Solubility——
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SMILESC1CO[Te](O1)(Cl)(Cl)Cl.[NH4+]
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Chemical NameAmmonium trichloro(dioxoethylene-O,O') tellurate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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