AS-252424

CAS No. 900515-16-4

AS-252424 ( AS252424; AS 252424; AS-252424 )

Catalog No. M16475 CAS No. 900515-16-4

AS-252424 is a potent and selective PI3Kγ inhibitor with an IC50 of 30±10 nM.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 41 In Stock
5MG 67 In Stock
10MG 123 In Stock
25MG 205 In Stock
50MG 309 In Stock
100MG 447 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    AS-252424
  • Note
    Research use only, not for human use.
  • Brief Description
    AS-252424 is a potent and selective PI3Kγ inhibitor with an IC50 of 30±10 nM.
  • Description
    AS-252424 is a potent and selective PI3Kγ inhibitor with an IC50 of 30±10 nM.
  • Synonyms
    AS252424; AS 252424; AS-252424
  • Pathway
    PI3K/Akt/mTOR signaling
  • Target
    PI3K
  • Recptor
    PI3Kγ; PI3Kα; Casein KiN/Ase 2
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    900515-16-4
  • Formula Weight
    305.28
  • Molecular Formula
    CHFNOS
  • Purity
    >98%(HPLC)
  • Solubility
    DMSO:30.5 mg/mL (100 mM)
  • SMILES
    O=C(NC/1=O)SC1=C/C2=CC=C(C3=CC=C(F)C=C3O)O2
  • Chemical Name
    (Z)-5-((5-(4-fluoro-2-hydroxyphenyl)furan-2-yl)methylene)thiazolidine-2,4-dione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Pomel V, et al. Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase gamma. J Med Chem. 2006 Jun 29;49(13):3857-71.
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