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AM9405
CAS No. ——
AM9405( AM-9405 | GAT379 | GAT-379 )
Catalog No. M17035 CAS No. ——
AM9405 (AM-9405, GAT-379) is novel potent, peripherally active cannabinoid type 1 (CB1) and 5-HT3 receptor agonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameAM9405
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NoteResearch use only, not for human use.
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Brief DescriptionAM9405 (AM-9405, GAT-379) is novel potent, peripherally active cannabinoid type 1 (CB1) and 5-HT3 receptor agonist.
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DescriptionAM9405 (AM-9405, GAT-379) is novel potent, peripherally active cannabinoid type 1 (CB1) and 5-HT3 receptor agonist, inhibits the EFS-induced twitch contraction of the ileum and the colon with IC50 of 0.076 and 45.71 nM, respectively; significantly slows mouse intestinal motility in physiological conditions, reverses hypermotility and reduced pain in mouse models mimicking symptoms of functional GI disorders, such as stress-induced diarrhea and writhing test.
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In Vitro——
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In Vivo——
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SynonymsAM-9405 | GAT379 | GAT-379
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PathwayGPCR/G Protein
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TargetCannabinoid Receptor
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RecptorCannabinoid Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight461.444
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Molecular FormulaC24H33BrN2O2
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name2-(2,6-dihydroxy-4-(2-methyloctan-2-yl)phenyl)-1,3-dimethyl-1H-benzo[d]imidazol-3-ium bromide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Salaga M, et al. Eur J Pharmacol. 2018 Aug 17;836:34-43.
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