AM9405

CAS No. ——

AM9405( AM-9405 | GAT379 | GAT-379 )

Catalog No. M17035 CAS No. ——

AM9405 (AM-9405, GAT-379) is novel potent, peripherally active cannabinoid type 1 (CB1) and 5-HT3 receptor agonist.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    AM9405
  • Note
    Research use only, not for human use.
  • Brief Description
    AM9405 (AM-9405, GAT-379) is novel potent, peripherally active cannabinoid type 1 (CB1) and 5-HT3 receptor agonist.
  • Description
    AM9405 (AM-9405, GAT-379) is novel potent, peripherally active cannabinoid type 1 (CB1) and 5-HT3 receptor agonist, inhibits the EFS-induced twitch contraction of the ileum and the colon with IC50 of 0.076 and 45.71 nM, respectively; significantly slows mouse intestinal motility in physiological conditions, reverses hypermotility and reduced pain in mouse models mimicking symptoms of functional GI disorders, such as stress-induced diarrhea and writhing test.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    AM-9405 | GAT379 | GAT-379
  • Pathway
    GPCR/G Protein
  • Target
    Cannabinoid Receptor
  • Recptor
    Cannabinoid Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    ——
  • Formula Weight
    461.444
  • Molecular Formula
    C24H33BrN2O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    2-(2,6-dihydroxy-4-(2-methyloctan-2-yl)phenyl)-1,3-dimethyl-1H-benzo[d]imidazol-3-ium bromide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Salaga M, et al. Eur J Pharmacol. 2018 Aug 17;836:34-43.
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