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AM-0902

CAS No. 1883711-97-4

AM-0902 ( —— )

Catalog No. M21665 CAS No. 1883711-97-4

AM-0902 is a potent and specific TRPA1 antagonist (IC50s: 71/131 nM for rTRPA1 and hTRPA1).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    AM-0902
  • Note
    Research use only not for human use.
  • Brief Description
    AM-0902 is a potent and specific TRPA1 antagonist (IC50s: 71/131 nM for rTRPA1 and hTRPA1).
  • Description
    AM-0902 is a potent and specific TRPA1 antagonist (IC50s: 71/131 nM for rTRPA1 and hTRPA1).
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    TRP/TRPV Channel
  • Recptor
    TRPA1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1883711-97-4
  • Formula Weight
    370.79
  • Molecular Formula
    C17H15ClN6O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 145 mg/mL (391.05 mM; Need ultrasonic and warming)
  • SMILES
    Cn(cn1)c2c1N=CN(Cc1nc(CCc(cc3)ccc3Cl)no1)C2=O
  • Chemical Name
    1-((3-(4-chlorophenethyl)-124-oxadiazol-5-yl)methyl)-7-methyl-17-dihydro-6H-purin-6-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Schenkel LB et al. Optimization of a Novel Quinazolinone-Based Series of Transient Receptor Potential A1 (TRPA1)Antagonists Demonstrating Potent in Vivo Activity. J Med Chem. 2016 Mar 24;59(6):2794-809.
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