AM-0561

CAS No. 1202764-63-3

AM-0561( AM0561 )

Catalog No. M10738 CAS No. 1202764-63-3

AM-0561 (AM0561) is a highly potent inhibitor of NF-κB inducing Kinase (NIK) with Ki of 0.3 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    AM-0561
  • Note
    Research use only, not for human use.
  • Brief Description
    AM-0561 (AM0561) is a highly potent inhibitor of NF-κB inducing Kinase (NIK) with Ki of 0.3 nM.
  • Description
    AM-0561 (AM0561) is a highly potent inhibitor of NF-κB inducing Kinase (NIK) with Ki of 0.3 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    AM0561
  • Pathway
    Apoptosis
  • Target
    NF-κB
  • Recptor
    NF-κB
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1202764-63-3
  • Formula Weight
    396.853
  • Molecular Formula
    C18H13ClN6OS
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(C#CC1=CN2C(=NC=C2C3=NC(=NC=C3Cl)N)C=C1)(C4=NC=CS4)O
  • Chemical Name
    (R)-4-(3-(2-amino-5-chloropyrimidin-4-yl)imidazo[1,2-a]pyridin-6-yl)-2-(thiazol-2-yl)but-3-yn-2-ol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Demchenko YN, et al. Oncotarget. 2014 Jun 30;5(12):4554-66.
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