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ALS-8112
CAS No. 1445379-92-9
ALS-8112( —— )
Catalog No. M33259 CAS No. 1445379-92-9
ALS-8112 (ALS 008112) is a selective and potent inhibitor of respiratory syncytial virus (RSV) polymerase with an IC50 value of 0.02 μM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 211 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameALS-8112
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NoteResearch use only, not for human use.
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Brief DescriptionALS-8112 (ALS 008112) is a selective and potent inhibitor of respiratory syncytial virus (RSV) polymerase with an IC50 value of 0.02 μM.
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DescriptionALS-8112 is a potent and selective respiratory syncytial virus (RSV) polymerase inhibitor. The 5'-triphosphate form of ALS-8112 inhibits RSV polymerase with an IC50 of 0.02 μM.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayJAK/STAT Signaling
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TargetSTAT
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RecptorRSV
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Research Area——
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Indication——
Chemical Information
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CAS Number1445379-92-9
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Formula Weight293.68
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Molecular FormulaC10H13ClFN3O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : ≥ 47 mg/mL (160.04 mM )
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SMILESNc1ccn([C@@H]2O[C@@](CO)(CCl)[C@@H](O)[C@H]2F)c(=O)n1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Wang G, et al. Discovery of 4'-chloromethyl-2'-deoxy-3',5'-di-O-isobutyryl-2'-fluorocytidine (ALS-8176), a first-in-class RSV polymerase inhibitor for treatment of human respiratory syncytial virus infection. J Med Chem. 2015 Feb 26;58(4):1862-78.?
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