
AG-14361
CAS No. 328543-09-5
AG-14361( AG14361 | AG-14361 | AG 14361. )
Catalog No. M14073 CAS No. 328543-09-5
AG14361 is a potent inhibitor of PARP1 with Ki of <5 nM. It is at least 1000-fold more potent than the benzamides.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
2MG | 59 | In Stock |
![]() ![]() |
5MG | 128 | In Stock |
![]() ![]() |
10MG | 233 | In Stock |
![]() ![]() |
25MG | 453 | In Stock |
![]() ![]() |
50MG | 660 | In Stock |
![]() ![]() |
100MG | 888 | In Stock |
![]() ![]() |
200MG | Get Quote | In Stock |
![]() ![]() |
500MG | Get Quote | In Stock |
![]() ![]() |
1G | Get Quote | In Stock |
![]() ![]() |
Biological Information
-
Product NameAG-14361
-
NoteResearch use only, not for human use.
-
Brief DescriptionAG14361 is a potent inhibitor of PARP1 with Ki of <5 nM. It is at least 1000-fold more potent than the benzamides.
-
DescriptionAG14361 is a potent inhibitor of PARP1 with Ki of <5 nM. It is at least 1000-fold more potent than the benzamides.
-
In Vitro——
-
In Vivo——
-
SynonymsAG14361 | AG-14361 | AG 14361.
-
PathwayCell Cycle/DNA Damage
-
TargetPARP
-
RecptorPARP1
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number328543-09-5
-
Formula Weight320.39
-
Molecular FormulaC19H20N4O
-
Purity>98% (HPLC)
-
SolubilityDMSO: 12 mg/mL (37.45 mM)
-
SMILESO=C1C2=C3C(N=C(C4=CC=C(CN(C)C)C=C4)N3CCN1)=CC=C2
-
Chemical Name1-(4-((dimethylamino)methyl)phenyl)-8,9-dihydro-2,7,9a-triazabenzo[cd]azulen-6(7H)-one.
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference



-
Rucaparib Camsylate
Rucaparib Camsylate is a PARP inhibitor (PARP1,Ki of 1.4 nM). Rucaparib Camsylate also displays binding affinity to eight other PARP domains. Rucaparib is the most effective PARP inhibitor in enzyme assays (Ki: 1.4 nM). Rucaparib inhibits PARP-1 activity by 97.1% at a concentration of 1 μM in permeabilized D283Med cells.
-
Fluzoparib
fluzoparib is a novel, potent, and orally available inhibitor of PARP, potentially for the treatment of solid tumours.Fluzoparib potently inhibited PARP1 enzyme activity and induced DNA double-strand breaks, G2 /M arrest, and apoptosis in homologous recombination repair (HR)-deficient cells.?
-
Rucaparib phosphate
An inhibitor of PARP with Ki of 1.4 nM for PARP1 in a cell-free assay.