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AD57

CAS No. 1093380-42-7

AD57( —— )

Catalog No. M33828 CAS No. 1093380-42-7

AD57 is a potent inhibitor of both c-Src and Abl with IC50 of 0.025 μM and 0.041 μM, respectively.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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10MG	212	Get Quote
25MG	347	Get Quote
50MG	495	Get Quote
100MG	659	Get Quote
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Biological Information

Product Name

AD57
Note

Research use only, not for human use.
Brief Description

AD57 is a potent inhibitor of both c-Src and Abl with IC50 of 0.025 μM and 0.041 μM, respectively.
Description

AD57 is an orally active multikinase inhibitor, inhibits RET, BRAF, S6K and Src, with greatly reduces mTOR activity.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Angiogenesis
Target

Src
Recptor

Src | Bcr-Abl
Research Area

——
Indication

——

Chemical Information

CAS Number

1093380-42-7
Formula Weight

455.44
Molecular Formula

C22H20F3N7O
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 125 mg/mL (274.46 mM; Ultrasonic )
SMILES

CC(C)n1nc(-c2ccc(NC(=O)Nc3cccc(c3)C(F)(F)F)cc2)c2c(N)ncnc12
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Dar AC, et al. Chemical genetic discovery of targets and anti-targets for cancer polypharmacology. Nature. 2012 Jun 6;486(7401):80-4. ?

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