AB-680

CAS No. 2105904-82-1

AB-680 ( —— )

Catalog No. M23955 CAS No. 2105904-82-1

AB-680 is a highly potent, reversible, and selective inhibitor of CD73 (an ectonucleotidase, Ki: 4.9 pM for hCD73) with anti-tumor activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 147 In Stock
5MG 222 In Stock
10MG 354 In Stock
25MG 592 In Stock
50MG 843 In Stock
100MG 1143 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    AB-680
  • Note
    Research use only, not for human use.
  • Brief Description
    AB-680 is a highly potent, reversible, and selective inhibitor of CD73 (an ectonucleotidase, Ki: 4.9 pM for hCD73) with anti-tumor activity.
  • Description
    AB-680 is a highly potent, reversible, and selective inhibitor of CD73 (an ectonucleotidase, Ki: 4.9 pM for hCD73) with anti-tumor activity, displays >10,000-fold selectivity over related ectonucleotidases CD39.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    CD73
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2105904-82-1
  • Formula Weight
    580.8
  • Molecular Formula
    C20H24ClFN4O9P2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:180 mg/mL (309.91 mM; Need ultrasonic)
  • SMILES
    C[C@@H](c(cccc1)c1F)Nc1cc(Cl)nc2c1cnn2[C@@H]([C@@H]1O)O[C@H](COP(CP(O)(O)=O)(O)=O)[C@H]1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Lawson KV, et al. Discovery and Characterization of AB680, a Potent and Selective Small-Molecule CD73 Inhibitor for Cancer Immunotherapy.
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