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8-Prenylnaringenin
CAS No. 53846-50-7
8-Prenylnaringenin ( —— )
Catalog No. M22019 CAS No. 53846-50-7
8-Prenylnaringenin is a phytoestrogen with high estrogenic activity,In vitro, aggregates of buccal epithelial cells were irradiated and cultured in suspension for 11 days.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 414 | In Stock |
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| 10MG | 608 | In Stock |
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| 25MG | 954 | In Stock |
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| 50MG | 1287 | In Stock |
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| 100MG | 1737 | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product Name8-Prenylnaringenin
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NoteResearch use only, not for human use.
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Brief Description8-Prenylnaringenin is a phytoestrogen with high estrogenic activity,In vitro, aggregates of buccal epithelial cells were irradiated and cultured in suspension for 11 days.
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Description8-Prenylnaringenin is a phytoestrogen with high estrogenic activity,In vitro, aggregates of buccal epithelial cells were irradiated and cultured in suspension for 11 days. 8-PN or TAM were investigated regarding their effect on cell shedding. In vivo, the lower tongue surface of mice was irradiated with graded single doses of 25 kV X-rays. The incidence, latency, and duration of the resulting mucosal ulcerations were analyzed after topical treatment with 8-PN, TAM or solvent. 8-PN or TAM prevented the volume reduction of the irradiated cell aggregates during the incubation period. This was the result of a higher residual cell number in the treated versus the untreated irradiated aggregates. In vivo, topical treatment with 8-PN or TAM significantly increased the latency of mucositis from 10.9 to 12.1 and 12.4 days respectively, while the ulcer incidence was unchanged.
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Synonyms——
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PathwayImmunology/Inflammation
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TargetROS
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RecptorROS
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Research Area——
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Indication——
Chemical Information
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CAS Number53846-50-7
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Formula Weight340.38
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Molecular FormulaC20H20O5
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Purity>98% (HPLC)
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Solubility——
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SMILESCC(C)=CCC1=C2O[C@@H](CC(=O)C2=C(O)C=C1O)C1=CC=C(O)C=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.8-prenylnaringenin and tamoxifen inhibit the shedding of irradiated epithelial cells and increase the latency period of radiation-induced oral mucositis : cell culture and murine model.Strahlenther Onkol. 2015 May;191(5):429-36.
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