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6-AZATHYMINE
CAS No. 932-53-6
6-AZATHYMINE( —— )
Catalog No. M22531 CAS No. 932-53-6
6-azathymine is a potent inhibitors of D-3-aminoisobutyrate-pyruvate aminotransferase.?6-Azauracil acted as a competitive inhibitor with respect to beta-alanine, and was an uncompetitive inhibitor with respect to pyruvic acid with a Ki of approximately 8.9 mM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | 57 | In Stock |
|
| 500MG | 113 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name6-AZATHYMINE
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NoteResearch use only, not for human use.
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Brief Description6-azathymine is a potent inhibitors of D-3-aminoisobutyrate-pyruvate aminotransferase.?6-Azauracil acted as a competitive inhibitor with respect to beta-alanine, and was an uncompetitive inhibitor with respect to pyruvic acid with a Ki of approximately 8.9 mM.
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Description6-azathymine is a potent inhibitors of D-3-aminoisobutyrate-pyruvate aminotransferase.?6-Azauracil acted as a competitive inhibitor with respect to beta-alanine, and was an uncompetitive inhibitor with respect to pyruvic acid with a Ki of approximately 8.9 mM.
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In Vitro6-Azathymine is a competitive antagonist of the growth of Streptococcus faecalis (8043) and several other strains of microorganisms. Studies of the mechanism of action of 6-Azathymine reveal that S. faecalis can convert the analog to the corresponding deoxyriboside, azathymidine.
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In VivoThe administration of 6-Azathymine to the mouse leads to the urinary elimination not only of free Azathymine, but also of various metabolites of it. Following the administration of 6-Azathymine-5-14C to mice, radioactivity is found in all tissues investigated, not only in the form of free Azathymine, but also as metabolic derivatives.
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Synonyms——
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorBacterial
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Research Area——
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Indication——
Chemical Information
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CAS Number932-53-6
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Formula Weight127.1
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Molecular FormulaC4H5N3O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (983.48 mM)
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SMILESCc1n[nH]c(=O)[nH]c1=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. N Tamaki, et al. Purification, Characterization and Inhibition of D-3-aminoisobutyrate Aminotransferase From the Rat Liver. Eur J Biochem. 1990 Apr 20;189(1):39-45.
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