Sortase-IN-6e

CAS No. 1809545-62-7

Sortase-IN-6e( —— )

Catalog No. M12774 CAS No. 1809545-62-7

A small molecule inhibitor of Staphylococcus aureus sortase with IC50 of 9.3 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Sortase-IN-6e
  • Note
    Research use only, not for human use.
  • Brief Description
    A small molecule inhibitor of Staphylococcus aureus sortase with IC50 of 9.3 uM.
  • Description
    A small molecule inhibitor of Staphylococcus aureus sortase with IC50 of 9.3 uM; blocks P2 precursor cleavage by sortase A with IC50 of 68.7 uM in staphylococci; does not affect in vitro staphylococcal growth yet protect mice against lethal S. aureus bacteremia.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1809545-62-7
  • Formula Weight
    381.36
  • Molecular Formula
    C14H8N5NaO3S2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    sodium 3-(3-(pyridin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)benzenesulfonate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zhang J, et al. Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13517-22.
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