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57-DIMETHOXYFLAVONE

CAS No. 21392-57-4

57-DIMETHOXYFLAVONE( —— )

Catalog No. M20412 CAS No. 21392-57-4

57-DIMETHOXYFLAVONE possessed remarkable leishmanicidal potential.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    57-DIMETHOXYFLAVONE
  • Note
    Research use only, not for human use.
  • Brief Description
    57-DIMETHOXYFLAVONE possessed remarkable leishmanicidal potential.
  • Description
    57-DIMETHOXYFLAVONE possessed remarkable leishmanicidal potential.
  • In Vitro
    Western Blot Analysis Cell Line:B16F10 melanoma cells Concentration:0-25 μM Incubation Time:48 h Result:Induced CREB phosphorylation, and inhibited Akt and GSK-3β phosphorylation.
  • In Vivo
    Animal Model:Aged mice Dosage:25 and 50 mg/kg Administration:p.o.Result:Increased grip strength and the running endurance.Increased muscle volume, weights, and cross-sectional area.Decreased serum and gastrocnemius muscle levels of IL-6 and TNF-α.
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Antifection
  • Recptor
    Antifection
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    21392-57-4
  • Formula Weight
    282.29
  • Molecular Formula
    C17H14O4?
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 62.5 mg/mL (221.40 mM)
  • SMILES
    COc1cc(OC)c2c(c1)oc(cc2=O)-c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Tasdemir D . Antitrypanosomal and antileishmanial activites of flavoids and their analogues : In vitro in vivo structure-activity relationship and quantitative structure-activity relationship studies[J]. Antimicrob Agents Chemother 2006 50(4):1352-1364.
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  • 57-DIMETHOXYFLAVONE

    57-DIMETHOXYFLAVONE possessed remarkable leishmanicidal potential.

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