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5-Benzyloxygramine

CAS No. 1453-97-0

5-Benzyloxygramine( —— )

Catalog No. M28056 CAS No. 1453-97-0

5-Benzyloxygramine blocks the Dopamin receptors and antagonizes the effects of 5-HT on the rat uterus and the rabbit ear.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    5-Benzyloxygramine
  • Note
    Research use only, not for human use.
  • Brief Description
    5-Benzyloxygramine blocks the Dopamin receptors and antagonizes the effects of 5-HT on the rat uterus and the rabbit ear.
  • Description
    5-Benzyloxygramine blocks the Dopamin receptors and antagonizes the effects of 5-HT on the rat uterus and the rabbit ear.(In Vitro):5-Benzyloxygramine is a new N protein PPI orthosteric stabilizer that exhibits both antiviral and N-NTD protein-stabilizing activities. 5-benzyloxygramine stabilizes the N-NTD dimers through simultaneous hydrophobic interactions with both partners, resulting in abnormal N protein oligomerization that was further confirmed in the cell.
  • In Vitro
    5-benzyloxygramine stabilizes the N-NTD dimers through simultaneous hydrophobic interactions with both partners, resulting in abnormal N protein oligomerization that was further confirmed in the cell.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Dopamine Receptor
  • Recptor
    AQP1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1453-97-0
  • Formula Weight
    280.371
  • Molecular Formula
    C18H20N2O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (891.71 mM)
  • SMILES
    CN(C)Cc1c[nH]c2ccc(OCc3ccccc3)cc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Seeliger D, et al. Discovery of novel human aquaporin-1 blockers. ACS Chem Biol. 2013 Jan 18;8(1):249-56.
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