5,6-Dihydrouridine

CAS No. 5627-05-4

5,6-Dihydrouridine( —— )

Catalog No. M33586 CAS No. 5627-05-4

5,6-Dihydrouridine, a modified base, is located in conserved positions within the D-loop of tRNA in Eukaryota, Bacteria, and some Archaea.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 53 Get Quote
5MG 77 Get Quote
10MG 117 Get Quote
25MG 181 Get Quote
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Biological Information

  • Product Name
    5,6-Dihydrouridine
  • Note
    Research use only, not for human use.
  • Brief Description
    5,6-Dihydrouridine, a modified base, is located in conserved positions within the D-loop of tRNA in Eukaryota, Bacteria, and some Archaea.
  • Description
    5,6-Dihydrouridine is a modified base found in conserved positions in the D-loop of tRNA in Bacteria, Eukaryota, and some Archaea.
  • In Vitro
    5,6-Dihydrouridine (Dihydrouridine) is one of the posttranscriptionally modified nucleosides. It is a product of the reduction of uridine (U), and can be further modified to 5-methyldihydrouridine (m5D). 5,6-Dihydrouridine is commonly present in the tRNA from Bacteria, Eukaryota, and some Archaea. It is identified in six positions in the “D-loop” of the tRNA (16, 17, 20a, 20b) and in position 47 in the variable loop.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Endogenous Metabolite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    5627-05-4
  • Formula Weight
    246.22
  • Molecular Formula
    C9H14N2O6
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 100 mg/mL (406.14 mM; Ultrasonic)DMSO : 35.71 mg/mL (145.03 mM; Ultrasonic )
  • SMILES
    OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1CCC(=O)NC1=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kasprzak JM, et al. Molecular evolution of dihydrouridine synthases. BMC Bioinformatics. 2012 Jun 28;13:153.?
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