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Home - Products - Proteasome/Ubiquitin - Endogenous Metabolite - 17-DIMETHYLXANTHINE

17-DIMETHYLXANTHINE

CAS No. 611-59-6

17-DIMETHYLXANTHINE ( Paraxanthine )

Catalog No. M19728 CAS No. 611-59-6

Paraxanthine is a metabolite of caffeine (sc-202514) which functions as an adenosine receptor ligand and a PARP-1 inhibitor in pulmonary epithelial cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    17-DIMETHYLXANTHINE
  • Note
    Research use only not for human use.
  • Brief Description
    Paraxanthine is a metabolite of caffeine (sc-202514) which functions as an adenosine receptor ligand and a PARP-1 inhibitor in pulmonary epithelial cells.
  • Description
    Paraxanthine is a metabolite of caffeine (sc-202514) which functions as an adenosine receptor ligand and a PARP-1 inhibitor in pulmonary epithelial cells. Studies suggest that Paraxanthine is structurally similar to caffeine and possibly mediates the physiological effects of caffeine. Also Paraxanthine acts as a competitive phosphodiesterase inhibitor which increases intracellular cAMP activates PKA inhibits TNF-α and leukotriene synthesis. In addition Paraxanthine acts as a Na+/K+ ATPase enzymatic effector.
  • Synonyms
    Paraxanthine
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Human Endogenous Metabolite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    611-59-6
  • Formula Weight
    180.16
  • Molecular Formula
    C7H8N4O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM;Water:1mg/mL
  • SMILES
    Cn1cnc2[nH]c(=O)n(C)c(=O)c12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Jiang M Kameda K Han L K et al. Isolation of lipolytic substances caffeine and 17-dimethylxanthine from the stem and rhizome of Sinomenium actum[J]. Planta Medica 1998 64(04):375-377.
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