4-amino-1,8-Naphthalimide

CAS No. 1742-95-6

4-amino-1,8-Naphthalimide( —— )

Catalog No. M22109 CAS No. 1742-95-6

4-amino-1,8-Naphthalimide (4-ANI) is a PARP inhibitor with IC50 of 180 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 35 In Stock
25MG 80 In Stock
50MG 132 In Stock
100MG 214 In Stock
200MG 318 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    4-amino-1,8-Naphthalimide
  • Note
    Research use only, not for human use.
  • Brief Description
    4-amino-1,8-Naphthalimide (4-ANI) is a PARP inhibitor with IC50 of 180 nM.
  • Description
    4-amino-1,8-Naphthalimide (4-ANI) is a PARP inhibitor with IC50 of 180 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    PARP
  • Recptor
    PARP
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1742-95-6
  • Formula Weight
    212.2
  • Molecular Formula
    C12H8N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Nc1ccc2C(=O)NC(=O)c3cccc1c23
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.SCHLICKER, A. 4-Amino-1,8-naphthalimide: a novel inhibitor of poly(ADP-ribose) polymerase and radiation sensitizer[J]. International Journal of Radiation Biology, 1999, 75(1):91-100.
molnova catalog
related products
  • OUL35

    OUL35 is a selective PARP-10 inhibitor, and small-molecule ARTD10 inhibitor. OUL35 has been shown to rescue cells from ARTD10-induced cell death.

  • Venadaparib

    Venadaparib (IDX-1197) is a potent, selective and orally active PARP inhibitor with IC50s of 1.4 nM and 1.0 nM for PARP1 and PARP2, respectively.

  • BYK204165

    BYK204165 is a potent PARP inhibitor?(PARP1; IC50 = 44.67 nM for human recombinant PARP1 in an enzyme assay).